Aydin H. Harston, Ph.D.
As a registered patent attorney, Dr. Aydin H. Harston concentrates his practice in intellectual property, focusing primarily on patent litigation, patent prosecution, post-grant proceedings and patent portfolio evaluations and opinions. Specifically, he routinely handles many aspects of patent prosecution, from pre-application counseling, to application preparation, worldwide filings, prosecution, and post-grant procedures. He also handles many aspects of patent litigation from discovery disputes, claim construction issues, expert witness preparations, to trial and appeals.
Since joining the firm in 2007, Dr. Harston has been involved in intellectual property matters covering an array of technological fields including: organic and inorganic chemistry; pharmaceutical patent prosecution and Hatch-Waxman litigations; herbicidal, fungicidal, and plant growth compositions; hydrocarbon recovery compositions and methods; OLEDs, LCDs and LEDs; laminates and films for solar and display devices; multiple sclerosis and cancer treatments; genetic engineering; recombinant DNA technology; imaging; robotic systems; medical devices and equipment; implants; polymer chemistry and product manufacturing; corrosion-prevention; aircraft and satellite technology; quantum cascade laser technologies; biological purification systems and methods; peptide and protein engineering; materials science; mechanical devices; contraceptive formulations and methods; devulcanization techniques; antihistamine and asthma drugs; vaccines; liposome-, vesicle-, microsponge- and bacterial ghost-encapsulated drugs; conveyor systems; lubricant formulations; electronic components; food science and nutraceuticals; isomeric drugs; deuterated drugs, prodrugs, printer inks and toners; and so forth.
Dr. Harston has prosecuted hundreds of patent applications in chemical, pharmaceutical, biotechnology, and mechanical fields and handled numerous IP due diligence projects. Dr. Harston has participated in litigation teams representing clients in Federal district courts and at the Court of Appeals for the Federal Circuit. Dr. Harston has also represented clients in reexamination proceedings before the U.S. Patent & Trademark Office.
Prior to joining Rothwell Figg, Dr. Harston researched protein structures, interactions, and dynamics using nuclear magnetic resonance (NMR) and other biochemical techniques. He also investigated and used novel protein expression and purification techniques, particularly for increasing the purified yield of isotope-labeled proteins. Dr. Harston’s dissertation focused on the molecular structures and interactions of proteins involved in cellular protein degradation pathways. His research was published in high impact journals including Nature Structural Molecular Biology and Molecular Cell. Dr. Harston also served in scientific, marketing and business development capacities at a start-up biotechnology firm in Maryland.
Areas of Concentration
Publications & Presentations
Co-author, "Long-Lived States to Monitor Protein Unfolding by Proton NMR" ChemPhysChem, 12(15), (2011): 2729–2734.
Co-author, Perturbing the Ubiquitin Pathway Reveals How Mitosis Is Hijacked to Denucleate and Regulate Cell Proliferation and Differentiation In Vivo, PLoS ONE, 5(10), (2010): e13331.
Co-Author, Structure of the S5a:K48 Linked Ubiquitin Complex and Its Interaction with Rpn13, Mol. Cell. 35(3), (2009):280-290.
Co-Author, Avid Interactions Underlie the K63-Linked Polyubiquitin Binding Specificities Observed for UBA Domains, Nature Struct. Mol. Biol. 16(8), (2009):883-889.
Haririnia, A. et al., Mutations in the Hydrophobic Core of Ubiquitin Differentially Affect its Recognition by Receptor Proteins, Journal of Molecular Biology 375, (2008):979-996.
Haririnia, A. et al., “Mapping the interactions between Lys48- and Lys63-linked di-ubiquitins and a ubiquitin-interacting motif of S5a” Journal of Molecular Biology 368, (2007):753-766.
Co-Author, “Personal Role Management: Overview and a Design Study of Email for University Students" Kaptelinin, V., Czerwinski, M. (Editors) Beyond the Desktop Metaphor, MIT Press, April 1, 2007.
Co-Author, “Solution conformation of Lys63-linked di-ubiquitin chain provides clues to functional diversity of polyubiquitin signaling” Journal of Biological Chemistry 279, (2004):7055-7063.
Professional Affiliations, Honors & Recognition
American Intellectual Property Law Association
Intellectual Property Owners Association
American Bar Association